The Effect of Vitamin D Supplementation on Insulin Sensitivity and Secretion in Prediabetes
by dr. Karen Denisa
| 01 August 2025
Several observational studies have shown that low blood levels of vitamin D are closely associated with an increased risk of type 2 diabetes. Although randomized clinical trials in individuals with prediabetes have not demonstrated a significant reduction in diabetes risk from vitamin D supplementation, recent meta-analyses suggest that vitamin D supplementation may help slow the progression to diabetes (with a relative risk reduction of 11%–12%) and increase the likelihood of returning to normal glucose regulation (with a relative benefit increase of 48%).