Composition:

Lansopazole.

Presentation:

Capsule 30 mg; Box of 2 strips x 10 capsules.

Pharmacology:

Lansoprazole act as gastric acid pump inhibitor, it suppresses gastric acid secretion by specific inhibition of the (H+, K+)-ATP ase (proton pump) of the parietal cells in the gastric mucosa.

Indications:

Duodenal ulcer, benign gastric ulcer, reflux oesophagitis.

Contraindications:

Hypersensitivity to Lansoprazole.

Dosage:

- Duodenal ulcer/reflux oesophagitis, recommended dose : 1 capsule daily for 4 weeks.

- Benign gastric ulcer, recommended dose : 1 capsule daily for 8 weeks.

- Elderly, hepatic disorder and renal insufficiency : dosage adjustment is not rewuired. Do not exceed 30 mg / day.

Lancid should be taken in the morning before food.

Warning and Precautions:

Caution is advised in prolonged use. Use in pregnancy and lactation : There are no adequate or well-controlled studies in pregnant woman. Lancid should not be used during preganncy only if clearly needed. A decision should be made whether to discontinue nursing or to discontinue the drug, taking into account the importance of the drug to mother. Safety and effectiveness in pediatric patients have not been establish.

Adverse Events:

- Headache (more than 1% of cases), diarrhea.

- Other side effects (less than 1%): Reactions similar to anaphylaxis, asthenia, candidiasis, chest pain (not specific), edema, fever, flu syndrome, halitosis, infection (non-specific), malaise

- Cardiovascular system: angina, cerebrovascular disorders, myocardial infarction, palpitations, shock (circulatory failure) - Digestive system: melena, digestive disorders, hematemesis, rectal bleeding, ulcerative colitis

- Endocrine diabetes mellitus, goiter system

- Hematological and lymphatic systems: pancytopenia, thrombotic thrombocytopenia purpura

- Metabolic Disorders: gout; Musculoskeletal system: arthritis, myalgia

- Nervous system: dizziness, hallucinations, hemiplegia, decreased libido, thinking disorders

- Respiratory system: asthma, pneumonia; Skin: acne, alopecia, rash

- Special senses: hearing loss, visual disturbances, taste disorders

- Urogenital system: abnormal menstruation, hematuria, impotence. Most haematological cases have not been clearly identified with lansoprazole.

LANCID