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Latest Articles
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Coenzyme Q10 and L-carnitine Supplementation for Weight Loss
by dr. Lyon Clement | 06 August 2026
Obesity is a major global health concern associated with metabolic, cardiovascular, musculoskeletal, and neoplastic disorders. Recent evidence suggests that mitochondrial dysfunction, oxidative stress, and chronic inflammation contribute to obesity pathogenesis, highlighting coenzyme Q10 (CoQ10) and L-carnitine as potential therapeutic supplements. This review evaluates the evidence supporting their roles in weight management. Preclinical studies demonstrated that CoQ10 supplementation improved lipid metabolism, reduced adipose tissue inflammation, oxidative stress, and fat accumulation in obese animal models. Clinical findings showed reduced CoQ10 levels in obese individuals, although evidence for direct weight-loss effects remains inconsistent. Conversely, CoQ10 has shown benefits in improving metabolic comorbidities such as non-alcoholic fatty liver disease and type 2 diabetes mellitus. L-carnitine promotes mitochondrial fatty acid β-oxidation and may enhance metabolic regulation through PPAR-γ activation and anti-inflammatory effects. Meta-analysis of 37 randomized controlled trials demonstrated significant reductions in body weight, body mass index, and fat mass following L-carnitine supplementation. Overall, CoQ10 and L-carnitine may support obesity management, particularly when combined with dietary, exercise, or other weight-loss interventions.
Use of Mesenchymal Stem Cells in Oculoplastic Surgery
by dr. Della Sulamita Mahendro, M.Kes (AAM), M.M, | 06 August 2026
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Benefits and Risks of Eating Cherries
by dr. Dita Arccinirmala | 03 August 2026
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Clopidogrel for Long-Term Maintenance Therapy Post-PCI: Evidence from HOST-EXAM 10Y
by dr. Alfredo Bambang, MBA | 24 July 2026
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Aggressive Therapy with Statin and Ezetimibe Combination in ASCVD Patients: Findings from the EZ-PAVE Study
by dr. Alfredo Bambang, MBA | 22 July 2026
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Basal Insulin Once a Week in Patients with Type 2 Diabetes Mellitus: What Are the Glycemic Control Outcomes?
by dr. Hastarita Lawrenti | 20 July 2026
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Cermin Dunia Kedokteran
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TRUXANTHIN
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As an exogenous and endogenous antioxidant
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STANZA
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Mefenamic acid 500 mg, works as an anti-inflammatory analgesic by inhibiting prostaglandin formation through inhibition of the cyclooxygenase enzyme
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NEVOX XR
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Metformin is an antihyperglycemic agent that improves glucose tolerance in type 2 diabetes patients
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EXCELOS INJECT is a synthetic bone graft material that can provide an osteoconductive effect.
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SERLOF
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Sertraline is a potent and specific serotonin reuptake inhibitor
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VOMINA
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Antiemetic effect can be achieved by gastro-kinetics peripheral antagonist effect on dopamine receptors on “Chemoreceptor triggered zone” which is positioned in post-rema area outside blood brain barrier.
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SEROLIN
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Nicergoline is a vasoactive drug, increasing the arterial flow and consumption of oxygen and glucose, reducing the vascular resistances of brain and lungs.
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PREGABALIN HJ
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Pregabalin binds highly to pain receptor of alpha2-delta in central nervous system for inhibiting over neural pain in one hour.
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CLAVAMOX
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Combination of beta-lactam antibotics with beta-lactamase inhibitors. Works to inhibit bacterial protein binding Penicillin.
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EFESA
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Efesa contains Efepoetin alpha (recombinant human erythropoietin-hybrid Fc fusion protein) which is a recombinant compound between two human erythropoietin molecules and hybrid FC region (hyFC®) fragment. It has advantages of low immunogenicity and longer half-life.
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