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Negative Pressure Wound Therapy Effectively Repairs Pressure Injury

dr. Nugroho Nitiyoso, MBA
Jul 02
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Updated 06/Jul/2021 .

Pressure injury/pressure sore is one of the most common types of chronic wounds. Pressure injury occurs due to high pressure on a limb with bony prominences due to prolonged bed rest.

Pressure injuries are divided according to their depth as follows:



One of the modalities studied to improve the condition of pressure injury is negative pressure wound therapy, with varying results. Dr. Song and the team from the PRC conducted a meta-analysis published in the journal Wound Repair Regen, 2021. In this meta-analysis, we evaluated data from 16 RCTs (randomized clinical trials), with a fundamental subject of 629 patients, performed on pressure injuries. Stages 3 and 4, and compared negative pressure wound therapy vs. standard wound care.


Parameters evaluated were wound healing time, pain score, and hospitalization cost. Result:

1. Wound healing duration was significantly shorter [WMD = -16.47 days, 95% [CI (-22.36 to –10.59) in the negative pressure wound therapy group than standard wound care.

2. Pain scores were significantly lower in the negative pressure wound therapy group than standard wound care (WMD = -2.39; 95%CI (−3.47 to -1.30), P 0.001].

3. Hospitalization costs were significantly lower in the negative pressure wound therapy group compared to standard wound care [SMD = -2.55; 95%CI (−4.07 to -1.03), P < 0.01].


Conclusion:

This meta-analysis concluded that the use of negative pressure wound therapy in pressure injury stage 3 or 4 could shorten the duration of wound healing, reduce pain, and reduce hospital costs.



Image: Illustration

Reference:

1. NPIAP. Pressure injury stages [Internet]. Available from: https://npiap.com/page/PressureInjuryStages

2. Song YP, Wang L, Yuan BF, Shen HW, Du L, Cai JY, Chen HL. Negative-pressure wound therapy for III/IV pressure injuries: A meta-analysis. Wound Repair Regen . 2021;29(1):20-33. doi:10.1111/wrr.12863. Epub 2020 Oct 12


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