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ACYCLOVIR OGB HJ

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    Komposisi:

    Acyclovir

    Bentuk sediaan:

    Tablet 200 mg & 400 mg: Box of 5 strips of x 10 tablets.

    Farmakologi:

    1) Inhibisi kompetitif terhadap DNA polymerase virus.

    2) Bergabung ke dalam dan memotong rantai DNA virus yang sedang bertumbuh.

    3) Inaktivasi DNA polymerase virus.

    Indikasi:

    - Infeksi herpes simplex pada kulit dan membran mukosa, pencegahan infeksi herpes simplex pada pasien immuno-compromised.

    - Infeksi herpes zoster.

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    Dosis:

    - Pengobatan dan pencegahan herpes simplex: 200 mg, 5 x sehari dengan interval 4 jam, selama 5 hari, dosis dapat ditingkatkan menjadi 400 mg.

    - Pengobatan herpes zoster : 800 mg, 5 kali sehari dengan interval 4 jam, selama 7 hari.

    - Anak ≥ 2 tahun : Sama dengan dosis dewasa.

    - Anak < 2 tahun : Diberikan setengah dosis dewasa.

    Kontraindikasi:

    Hipersensitif terhadap Acyclovir.

    Peringatan dan Perhatian:

    Hati-hati pemberian pada wanita yang sedang menyusui.

    Efek Samping:

    - Gatal-gatal / skin rash.

    - Gangguan gastrointestinal, termasuk: nausea, vomiting, diare, dan nyeri abdominal.

    - Peningkatan sementara enzym hati, peningkatan urea darah dan kreatinin; sakit kepala, reaksi neurologis dan fatigue.

    Interaksi Obat:

    -

     

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    ACYCLOVIR OGB HJ

     

    Composition:

    Acyclovir

    Presentation:

    Tablet 200 mg & 400 mg: Box of 5 strips of x 10 tablets

    Pharmacology:

    1) Competitive inhibition of the DNA polymerase virus.

    2) Join inside and cut the growing DNA chain of the virus.

    3) Inactivation of DNA polymerase virus.

    Indications:

    - Herpes simplex infection of the skin and mucous membranes, prevention of herpes simplex infection in immuno-compromised patients.

    - Shingles infection.

    Contraindications:

    Hypersensitivity to Acyclovir.

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    Dosage:

    - Treatment and prevention of herpes simplex: 200 mg, 5 times a day at 4-hour intervals, for 5 days, the dose can be increased to 400 mg.

    - Treatment of herpes zoster: 800 mg, 5 times a day at 4 hour intervals, for 7 days.

    - Children = 2 years: Same as adult doses.

    - Children <2 years old: Given half an adult dose.

    Warning and Precautions:

    Beware of giving to women who are breastfeeding.

    Adverse events:

    - Itching / skin rash.

    - Gastrointestinal disorders, including: nausea, vomiting, diarrhea, and abdominal pain.

    - transient increase in liver enzymes, increase in blood urea and creatinine; headaches, neurological reactions and fatigue.

    Drugs Interaction:

    -

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