Oleh admin kalbemed pada June 04, 2018 06:00

Polihexanide Bermanfaat Menurunkan Kejadian Infeksi Luka

Infeksi luka adalah salah satu komplikasi yang sering terjadi. Infeksi terjadi apabila ada bakteri yang masuk ke luka kemudian bakteri tersebut berkembang biak dan berakibat pada respons peradangan dari tubuh. Karena infeksi tersebut maka luka akan terus tertahan pada fase peradangan dan tidak bisa masuk ke fase proliferasi.

Sedangkan, penyembuhan luka paling banyak terjadi pada fase proliferasi. Oleh karena itu, apabila seorang individu mengalami luka, maka sangat penting untuk mencegah infeksi. Beberapa cairan antiseptik telah digunakan secara luas oleh para tenaga kesehatan untuk mencuci luka dengan tujuan untuk mencegah infeksi luka. Di antara beberapa cairan antiseptik untuk mencuci luka antara lain: Polihexanide, Povidone Iodine, Hidrogen Peroksida dan Larutan Ringer.

Tim Peneliti dari Switzerland melakukan sebuah penelitian kohort. Penelitian kohort ini memfollow-up pasien yang datang berobat dengan luka dan dilakukan pencucian luka menggunakan Povidone Iodine, Larutan Ringer, Hidrogen Peroksida dan Polihexanide sejak tahun 1973 sampai 2005 (tiga puluh tahun). Parameter yang dievaluasi adalah persentase pasien yang mengalami infeksi jaringan luka sepanjang perawatan.

Hasilnya didapatkan bahwa angka infeksi jaringa lunak sepanjang perawatan setelah pencucian luka menggunakan antiseptik sebesar: 1,7% (Polihexanide 0,04%), 4,8% (Povidone Iodine 1%), 5,9% (larutan Ringer) dan 11,7% (hydrogen peroksida). Kelompok pasien yang mengalami pencucian luka menggunakan polihexanide mengalami kejadian infeksi yang paling rendah di antara semua kelompok antiseptik, secara bermakna. [NNO]


Image: Ilustrasi
Referensi:  Roth B, Neuenschwander R, Brill F, Wurmitzer F, Wegner C, Assadian O, et al. Effect of antiseptic irrigation on infection rates of traumatic soft tissue wounds: a longitudinal cohort study. J Wound Care. 2017 Mar 2;26(3):79–87.


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chan yuan
## chan yuan
Thursday, June 07, 2018 3:13 PM
chanyuan2018.06.07

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