Oleh admin kalbemed pada January 03, 2018 06:00

Probiotik Berpotensi Mempunyai Efek Antioksidan

Probiotik didefinisikan sebagai mikroorganisme hidup yang jika dikonsumsi dalam jumlah tertentu memberikan manfaat  terhadap kesehatan pejamu.  Beberapa manfaat probiotik antara lain  mencegah dan menurunkan kejadian diare, memperbaiki kesetimbangan flora kesehatan saluran cerna, IBS, IBD,  memperbaiki intoleransi laktosa,  meningkatkan potensi imunitas, dsb.

Studi yang lebih baru yaitu  menunjukkan probiotik mempunayi potensi efek antioksidan,  sehingga probiotik mampu menurunkan jumlah/ akumulasi radikal bebas dan  menurunkan stres akibat oksidatif.

Efek antioksidatif dari Bifidobacterium longum and Lactobacillus acidophilus ditunjukkan dengan penghambatan  peroksidasi  asam linoleat sekitar  28–48% studi lain sekitar 38 – 46%.  Data ini menunjukkan  bahwa kedua bakteri asam laktat tersebut  mempunyai potensi sebagai antioksidan yang baik. Bifidobacterium longum and Lactobacillus acidophilus  juga menunjukkan  mempunyai kemampuan untuk mengikat radikal bebas  , -diphenyl-β-picrylhydrazyl (DPPH) sekitar 21–52%. Juga menunjukkan kemampuan menghambat efek sitotoksik dari 4-nitroquinoline-N-oxide (4NQO). Efek sitotoksik 4NQO dihambat oleh Lactobacillus acidophilus sekitar 50% dan sekitar 90% oleh Bifidobacterium longum.

Efek  Bifidobacterium longum and Lactobacillus acidophilus  terhadap penghambatan peroksidasi lemak juga dievaluasi, yang menunjukkan bahwa kedua bakteri tersebut mampu menghambat peroksidase lemak sekitar 11% sampai 29%  untuk 109 cells  dari  Bifidobacterium longum dan Lactobacillus acidophilus.

Kesimpulan, secara umum Bifidobacterium longum dan Lactobacillus acidophilus menunjukkan kemampuan  sebagai antioksidatif dan lebih kuat pada Bifidobacterium longum.


Image: Ilustrasi
Referensi.
1. Songisepp, E. et al.  A New Probiotic Cheese with Antioxidative and Antimicrobial Activity. J. Dairy Sci. 87:2017-2023. (Abstract)
2. Meei-Yn Lin, et al. Antioxidative Effect of Intestinal Bacteria Bifidobacterium longum ATCC 15708 and Lactobacillus acidophilus ATCC 4356.  Digestive Diseases and Sciences. Issue:  Volume 45, Number 8.  August 2000 .Pages: 1617 (abstract).
3. Lin MY. Inhibition of lipid peroxidation by Lactobacillus acidophilus and Bifidobacterium longum. J Agric Food Chem. 1999 Sep;47(9):3661. (abstract).

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