Oleh admin kalbemed pada December 07, 2017 06:00

Bakteri Usus, Adakah Manfaat Terhadap Kesehatan Tulang?

Dalam beberapa tahun terakhir, telah muncul fakta baru bahwa ketidakseimbangan baik kuantitatif maupun kualitatif dari mikrobiota ataupun bakteri usus mampu mempengaruhi kesehatan terkait dengan sejumlah keadaan yang abnormal seperti penyakit radang usus atapun gangguan usus yang lain.

Selain efek  lokal pada organ usus, telah muncul bukti  yang menunjukkan potensi mikrobiota mampu memperbaiki kesehatan tulang secara keseluruhan melalui fenomena sumbu tulang-usus. Hal itu terungkap pada artikel yang disampaikan oleh Fraser L. Collins dari Department of Physiology Michigan State University East Lansing USA dalam artikelnya yang telah dipublikasikan dalam jurnal Toxicology baru-baru ini.

Dalam artikel tersebut, dibahas bagaimana diet ataupun asupan nutrisi dapat mempengaruhi komposisi mikrobiota ataupun mikroflora usus, melalui asupan prebiotik, dan bagaimana ini digunakan oleh bakteri untuk mempengaruhi sistem kekebalan dan memperbaiki tulang secara keseluruhan.

Selain itu, peneliti tersebut juga merinci tentang hasil penelitian  terbaru dari hewan pengerat yang menyelidiki bagaimana dampak suplementasi probiotik dapat meningkatkan kepadatan mineral tulang pada hewan  "sehat" dan melindungi dari kehilangan  ataupun pengeroposan tulang yang bersifat patologis terkait dengan kekurangan estrogen pada  kondisi menopause. Dalam artikel tersebut juga disoroti tentang kemajuan dalam hal dalam menggali mekanisme yang berpotensi menyebabkan efek menguntungkan yang terjadi pada suplementasi prebiotik, probiotik terhadap kesehatan tulang. (Red)



Image: Ilustrasi
Referensi: Fraser L. Collins; Soon Mi Kim; Laura R. McCabe; Connie M. Weaver. Intestinal Microbiota and Bone Health: The Role of Prebiotics, Probiotics, and Diet Bone Toxicology pp 417-443

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