Oleh admin kalbemed pada August 08, 2017 06:30

Vitamin D Dosis Tinggi Bermanfaat pada "Sunburn"

Suatu studi yang dipublikasikan dalam Journal of Investigative Dermatology menemukan bahwa konsumsi dosis tinggi vitamin D3 satu jam setelah sunburn dapat secara bermakna menurunkan kemerahan, pembengkakan dan inflamasi pada kulit. Studi ini merupakan studi pertama yang menggambarkan manfaat antiinflamasi akut dari konsumsi vitamin D.

Studi acak dan tersamar ganda dengan kontrol plasebo ini dilakukan oleh para peneliti dari Case Western Reserve University School of Medicine and University Hospitals Cleveland Medical Center pada 20 subjek yang secara acak mendapat vitamin D3 (cholecalciferol) 50.000 IU, 100.000 IU, atau 200.000 IU atau plasebo, satu jam setelah “experimental sunburn” kecil melalui lampu UV pada lengan bagian dalam. Kemudian subjek diperiksa setelah 24 jam, 48 jam, 72 jam, dan 1 minggu setelah eksperimen, dan juga dilakukan biopsi kulit untuk pengujian selanjutnya.

Hasil studi menemukan bahwa subjek yang mengkonsumsi dosis tertinggi vitamin D mempunyai manfaat jangka panjang, termasuk penurunan inflamasi kulit 48 jam setelah sunburn. Kelompok dosis 200.000 IU menunjukkan penurunan ekspresi mediator proinflamasi TNF-alpha (p=0,04) dan iNOS (p=0,02) pada sampel biopsi kulit setelah sunburn.

Lebih lanjut, subjek dengan kadar vitamin D3 serum tertinggi setelah terapi (p=0,007) menunjukkan penurunan kemerahan kulit (p=0,02) dan peningkatan ekspresi arginase-1, suatu enzim antiinflamasi, yang menunjukkan peningkatan proses perbaikan barier kulit. Upregulasi arginase-1 dianggap menjadi mekanisme baru vitamin D dalam membantu perbaikan jaringan setelah kerusakan dan mengaktivasi protein antiinflamasi. Subjek dengan kadar vitamin D3 serum lebih rendah menunjukkan kadar gen proinflamasi yang bermakna.

FDA saat ini merekomendasikan vitamin D 400 IU per hari untuk dewasa, tetapi dosis yang diteliti dalam studi ini lebih tinggi dibanding dengan kebutuhan yang dianjurkan. Meskipun tidak dianjurkan mulai konsumsi vitamin D setelah sunburn berdasarkan pada studi ini saja, namun hasil studi ini menjanjikan dan layak untuk diteliti lebih lanjut.(EKM)



Image: Ilustrasi
Referensi:
1. Han DH. High-dose vitamin D may benefit skin after sunburn [Internet]. 2017 [cited 2017 July 10]. Available from: http://www.empr.com/news/vitamin-d3-sunburn-skin-redness-swelling-cholecalciferol/article/673658/
2. Vitamin D may improve sunburn, according to new clinical trial [Internet]. 2017 [cited 2017 July 10]. Available from: https://www.sciencedaily.com/releases/2017/07/170706125020.htm
3. Scott JF, Das LM, Ahsanuddin S, Qiu Y, Binko Am, Traylor ZP et al. Oral vitamin D rapidly attenuates inflammation from sunburn: an interventional study. J Invest Dermatol. 2017. DOI: 10.1016/j.jid
.2017.04.040

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As Vito is currently the main Louboutin Pas Cherfactory shop discount, so the following are based on the factory shop style, boutique Burberry Outletstyle after the experience and then add it.

Coach Factory Outlets:Coach Outletfactory shop and we usually visit the same shopping malls, and then checkout, the factory shop in the F starting goods because it is special for the discount,Guess Outlet so there is no dust bag. Is such a package,Coach OutletVito get a naked package, there is no packaging, often buyers can ask a paper bag,Nike Air MaxVito's answer is that we really do not have paper bags, ah, the first time to buy a 10 package to buy 1 bag, followed by our recent Moncler Jacketsofficial website to buy more, the official website is certainly not to the bag. The The

And the store to buy, there will be a small ticket, the current Coach Red Bottom Shoesbuyers will be additional businessmen want to shop a small gift, each bag regardless of the size of the North Face Jacketscorresponding one, gift small ticket is Burberry Scarfactually a very intimate design, above All the purchase of information, but no price, indicating that foreigners are also very taboo to let the other North Face Outletsee the price of things ~ This is undoubtedly Nike Air Max Pas Chera gambling for the purchasingmen, so there are good credentials, and do not have to tell the real Tory Burch Outletprice Buyers (even if only earn a little bit, it is estimated that all buyers are not balanced inside, hey)

But now the black heart North Face Outletof the means of business more and more clever, not to say that there must be a small ticket is true,Nike Hoodies

[Vito US purchasing] Coach bag true and false to identify Michael Kors Handbagsa little personal experience ~


First of all, starting from the Coach Outlet Onlinesmall ticket itself, it should be thermal paper, the front of the Coach size Logo, the True Religion OutletVito has seen from friends over there fake small ticket. How do we want to see a Kate Spade Outletsmall ticket, to learn about it.opposite has a variety of English description, in short, is basically nothing blank, paper is thin, feeling even a little North Face Outletthrough, from top to bottom The information is: the sale of the store address and the phone (this can be found online),Red Bottom Shoesand then is the store code, registration number, salesperson name, this part we really can not tell any useful information, then then Coach Outlet Onlinelook down, The following is the main event, first of all, GIFT RECEIPT that this is a gift small ticket, and then the goods referred to Kate Spadeas "ASHLEY LTH CRYL", also wrote in the lower part of the tag. This is the name of the package abbreviation,UGG Outletsuch as the final CRYL = CARRYALL this package has the corresponding style, the general is relatively large handbag, not Mummy bag, will not be a backpack, not a messenger bag. And then a string of 88 **** 53, Vito guess the goods number of the business, for management,Coach Factory Outlet we generally do not see the number in the mall,True Religionbut because it is used for management is not used for external display, Vito think Nike Air Maxof Will it be the same as AF? Before the introduction, AF piracy is not scanning the bar North Face Outletcode, vito hand without coach fake, so I have not tried the same can not be the same as the model, if you look at the appropriate examples may wish to Air Jordan Pas Chersend a vito, In addition, the same style, with a color number of the goods should be the same code, do not worry can be found in Burberry OutletTaobao a tag to compare the look, look at the bar Red Bottom Shoescode out of the corresponding number of right And then down is the number,Michael Korscolor, the number of the. Basic lack of reference.



There are also a lot of children's shoes to ask is that the general bag inYeezy Boost 350 v2the zipper are generally under the cortex of the factory chapter, this almost every big bag will have, the Burberry Outletabove will indicate the origin, the other will Christian Louboutin Outlethave a number below, in front of the part Description of the production batch, but the specific rules of vito not yet understand, but it is certain Kate Spade Outletthat this number Red Bottom Shoesis not unique, that is, a style of the package, within the leather with the above number may be completely consistent! Because it is the same batch of production! Behind the beginning Scarpe Nike Air Maxof the F or the number, should be and small ticket, tag exactly Louis Vuitton Outletthe same.

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