Oleh Admin Kalbe Medical pada February 07, 2017 07:30

Inhalasi Kortikosteroid dan Betaagonis Tidak Menyebabkan Karies pada Anak dengan Asma

Asma adalah penyakit inflamasi kronik saluran napas bawah yang ditandai oleh episode berulang dari batuk, sesak napas, dada tertekan, dan wheezing. Pada pasien asma dapat terjadi eksaserbasi, atau dikenal juga dengan serangan asma, yaitu kejadian di mana gejala asma yang dialami pasien secara mendadak menjadi lebih berat. Gejala-gejala ini dapat berakibat menurunnya kualitas hidup.

Asma juga adalah penyakit yang banyak mengenai anak-anak. Asma adalah penyakit kronik yang paling banyak terjadi pada anak. Akan tetapi, pengobatan asma pada anak sedikit berbeda dengan pengobatan asma pada dewasa, di mana anak-anak lebih sulit untuk menggunakan pengobatan inhalasi dan lebih mudah menggunakan pengobatan oral. Ditambah dengan faktor pengobatan asma yang biasanya cukup lama dan dapat beberapa tahun, maka ada kekhawatiran bahwa dapat mengakibatkan karies pada gigi anak.


Untuk mengetahui apakah pengobatan asma dapat mengakibatkan karies pada gigi anak, maka dr. Heidari dan tim dari Iran melakukan sebuah penelitian cross-sectional pada pasien asma anak. Sebanyak 85 anak usia 3 sampai 12 tahun dengan asma, dievaluasi riwayat pengobatannya untuk mengetahui seberapa banyak penggunaan obat oral dan penggunaan obat inhalasinya. Kemudian setiap anak juga mendapat evaluasi dari dokter gigi, untuk mengevaluasi seberapa banyak terjadinya caries, dan dievaluasi adanya hubungan antara pengobatan dan karies.


Hasilnya, diketahui bahwa terdapat hubungan bermakna di mana semakin banyak anak menelan tablet cetirizine atau ketotifen, maka semakin besar risiko kejadian karies pada anak tersebut (p=0,006). Sedangkan diketahui juga bahwa penggunaan spray inhalasi, baik jenis ß2 agonis, antihistamin, steroid atau kombinasinya, ternyata tidak berpengaruh terhadap risiko terjadinya karies (p=0,907).


Kesimpulan:
Para orangtua pasien tidak perlu khawatir bahwa penggunaan inhalasi fluticasone salmeterol akan menyebabkan karies gigi, karena menurut penelitian cross-sectional ini, penggunaan inhalasi kombinasi beta2 agonis + steroid tidak menambah risiko karies gigi pada anak. (NNO)

Image : Ilutrasi
Referensi:
1.Global Initiative for Asthma [Internet]. Global Initiative for Asthma - GINA. [cited 2016 Jul 27]. Available from: http://ginasthma.org/
2.Heidari A, Seraj B, Shahrabi M, Maghsoodi H, Kharazifard MJ, Zarabian T. Relationship between different types and forms of anti-asthmatic medications and dental caries in three to 12 year olds. J Dent Tehran Iran. 2016;13(4):238–43.

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